Anti-thymocyte serum effects on Plasmodium berghei infection in rats
Rabbit anti-rat thymocyte serum (ATS) virtually abolished the innate resistance mechanism(s) of rats of different ages to primary infection with Plasmodium berghei . ATS apparently produced its immunosuppressant effect without arresting humoral antibody production as judged by agar-gel double diffus...
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| Veröffentlicht in: | Immunology 1970-11, Vol.19 (5), p.759-766 |
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| creator | Spira, D T Silverman, P H Gaines, C |
| description | Rabbit anti-rat thymocyte serum (ATS) virtually abolished the innate resistance mechanism(s) of rats of different ages to primary infection with
Plasmodium berghei
. ATS apparently produced its immunosuppressant effect without arresting humoral antibody production as judged by agar-gel double diffusion tests. These results, when considered together with those of other workers, suggest that cell-mediated immunity is substantially involved in resistance to
P. berghei
. |
| format | Article |
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Plasmodium berghei
. ATS apparently produced its immunosuppressant effect without arresting humoral antibody production as judged by agar-gel double diffusion tests. These results, when considered together with those of other workers, suggest that cell-mediated immunity is substantially involved in resistance to
P. berghei
.</description><identifier>ISSN: 0019-2805</identifier><identifier>EISSN: 1365-2567</identifier><identifier>PMID: 4991884</identifier><language>eng</language><publisher>England</publisher><subject>Age Factors ; Animals ; Antibody Formation ; Female ; Immune Sera ; Immunity, Cellular ; Immunodiffusion ; Immunosuppressive Agents ; Malaria - immunology ; Rabbits ; Rats ; Reticulocytes ; Thymus Gland - immunology</subject><ispartof>Immunology, 1970-11, Vol.19 (5), p.759-766</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1455636/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1455636/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4991884$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Spira, D T</creatorcontrib><creatorcontrib>Silverman, P H</creatorcontrib><creatorcontrib>Gaines, C</creatorcontrib><title>Anti-thymocyte serum effects on Plasmodium berghei infection in rats</title><title>Immunology</title><addtitle>Immunology</addtitle><description>Rabbit anti-rat thymocyte serum (ATS) virtually abolished the innate resistance mechanism(s) of rats of different ages to primary infection with
Plasmodium berghei
. ATS apparently produced its immunosuppressant effect without arresting humoral antibody production as judged by agar-gel double diffusion tests. These results, when considered together with those of other workers, suggest that cell-mediated immunity is substantially involved in resistance to
P. berghei
.</description><subject>Age Factors</subject><subject>Animals</subject><subject>Antibody Formation</subject><subject>Female</subject><subject>Immune Sera</subject><subject>Immunity, Cellular</subject><subject>Immunodiffusion</subject><subject>Immunosuppressive Agents</subject><subject>Malaria - immunology</subject><subject>Rabbits</subject><subject>Rats</subject><subject>Reticulocytes</subject><subject>Thymus Gland - immunology</subject><issn>0019-2805</issn><issn>1365-2567</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1970</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkE1LxDAQhoMo67r6E4SevBXy0aSTi7D4DQt60HPJptPdSJusSSrsv7fiIsochplneF6YIzJnQsmSS1UfkzmlTJccqDwlZym9T6OgUs7IrNKaAVRzcrv02ZV5ux-C3WcsEsZxKLDr0OZUBF-89CYNoXXTdo1xs0VXOP9N3QSdL6LJ6ZycdKZPeHHoC_J2f_d681iunh-ebparcscVyyUosLWUxvBKtdwysIaCblmrkQuJCMKCVW1NYSqLXNfQacoNp0YBahALcv3j3Y3rAVuLPkfTN7voBhP3TTCu-U-82zab8NmwSkol1CS4Oghi-Bgx5WZwyWLfG49hTA1UtRBasunw8m_Sb8Thb-IL68xrpQ</recordid><startdate>197011</startdate><enddate>197011</enddate><creator>Spira, D T</creator><creator>Silverman, P H</creator><creator>Gaines, C</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>197011</creationdate><title>Anti-thymocyte serum effects on Plasmodium berghei infection in rats</title><author>Spira, D T ; Silverman, P H ; Gaines, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p261t-868c755aa246d2c18ca089d1d9e235ee83c8c6d708080ce2978f902a20a68e983</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1970</creationdate><topic>Age Factors</topic><topic>Animals</topic><topic>Antibody Formation</topic><topic>Female</topic><topic>Immune Sera</topic><topic>Immunity, Cellular</topic><topic>Immunodiffusion</topic><topic>Immunosuppressive Agents</topic><topic>Malaria - immunology</topic><topic>Rabbits</topic><topic>Rats</topic><topic>Reticulocytes</topic><topic>Thymus Gland - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Spira, D T</creatorcontrib><creatorcontrib>Silverman, P H</creatorcontrib><creatorcontrib>Gaines, C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Immunology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Spira, D T</au><au>Silverman, P H</au><au>Gaines, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Anti-thymocyte serum effects on Plasmodium berghei infection in rats</atitle><jtitle>Immunology</jtitle><addtitle>Immunology</addtitle><date>1970-11</date><risdate>1970</risdate><volume>19</volume><issue>5</issue><spage>759</spage><epage>766</epage><pages>759-766</pages><issn>0019-2805</issn><eissn>1365-2567</eissn><abstract>Rabbit anti-rat thymocyte serum (ATS) virtually abolished the innate resistance mechanism(s) of rats of different ages to primary infection with
Plasmodium berghei
. ATS apparently produced its immunosuppressant effect without arresting humoral antibody production as judged by agar-gel double diffusion tests. These results, when considered together with those of other workers, suggest that cell-mediated immunity is substantially involved in resistance to
P. berghei
.</abstract><cop>England</cop><pmid>4991884</pmid><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0019-2805 |
| ispartof | Immunology, 1970-11, Vol.19 (5), p.759-766 |
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| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Age Factors Animals Antibody Formation Female Immune Sera Immunity, Cellular Immunodiffusion Immunosuppressive Agents Malaria - immunology Rabbits Rats Reticulocytes Thymus Gland - immunology |
| title | Anti-thymocyte serum effects on Plasmodium berghei infection in rats |
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