Tree scanning: a method for using haplotype trees in phenotype/genotype association studies

We use evolutionary trees of haplotypes to study phenotypic associations by exhaustively examining all possible biallelic partitions of the tree, a technique we call tree scanning. If the first scan detects significant associations, additional rounds of tree scanning are used to partition the tree i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genetics (Austin) 2005, Vol.169 (1), p.441-453
Hauptverfasser:	Templeton, A.R, Maxwell, T, Posada, D, Stengard, J.H, Boerwinkle, E, Sing, C.F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adh gene Adh locus alcohol dehydrogenase Alcohol Dehydrogenase - genetics Alleles Animals Apolipoproteins E - genetics Biological Evolution Drosophila melanogaster Drosophila melanogaster - genetics Drosophila melanogaster - metabolism Female Gene loci Genes genetic techniques and protocols Genetic testing Genetic Variation Genotype Genotype & phenotype haplotypes Haplotypes - genetics Investigations loci Male Phenotype Polymorphism, Single Nucleotide Restriction Mapping Tests tree scanning
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!