Human centromeric alphoid domains are periodically homogenized so that they vary substantially between homologues. Mechanism and implications for centromere functioning

Sequence analysis of alphoid repeats from human chromosomes 17, 21 and 13 reveals recurrent diagnostic variant nucleotides. Their combinations define haplotypes, with higher order repeats (HORs) containing identical or closely-related haplotypes tandemly arranged into separate domains. The haplotype...

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Veröffentlicht in:	Nucleic acids research 2006-01, Vol.34 (6), p.1912-1924
1. Verfasser:	Roizes, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Centromere - chemistry Centromere - metabolism Chromosomes, Human, Pair 13 - chemistry Chromosomes, Human, Pair 17 - chemistry Chromosomes, Human, Pair 21 - chemistry DNA, Satellite - chemistry Genetics Haplotypes Human genetics Humans Life Sciences Sequence Analysis, DNA Sequence Homology, Nucleic Acid
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