Effects of single daily doses of a pyridil-2-tetrahydrothiophene derivative (40749 RP) on 24 hour H+ activity, nocturnal acid output, gastrin and pepsinogen I profiles in duodenal ulcer patients

40749 RP is a pyridil-2-tetrahydrothiophene derivative, belonging to a new class of gastric antisecretory drugs. We compared its effects on gastric secretion with cimetidine. Intragastric acidity, nocturnal acid output, gastrin and pepsinogen-I profiles were measured in patients with duodenal ulcer...

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Veröffentlicht in:	Gut 1986-04, Vol.27 (4), p.423-426
Hauptverfasser:	Malè, P J, Griessen, M, Cunningham, M G, Frydman, A M, Garoflid-Oprescu, N A, De Peyer, R, Loizeau, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-Ulcer Agents - pharmacology Biological and medical sciences Cimetidine - pharmacology Depression, Chemical Digestive system Drug Evaluation Duodenal Ulcer - metabolism Gastric Acid - metabolism Gastric Juice - metabolism Gastrins - metabolism Humans Hydrogen-Ion Concentration Male Medical sciences Pepsinogens - metabolism Pharmacology. Drug treatments Thiophenes - pharmacology Time Factors
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