Gastrocytoprotection by colloidal bismuth subcitrate (De-Nol) and sucralfate. Role of endogenous prostaglandins

This study compares the gastroprotective effects of colloidal bismuth subcitrate (De-Nol) with those of sucralfate and a methylated analogue of prostaglandin E2 (PGE2) against acute gastric lesions induced by acidified aspirin and absolute ethanol in rats. Both De-Nol and sucralfate given orally pre...

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Veröffentlicht in:	Gut 1987-02, Vol.28 (2), p.201-205
Hauptverfasser:	Konturek, S J, Radecki, T, Piastucki, I, Brzozowski, T, Drozdowicz, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aspirin Biological and medical sciences Digestive system Dinoprostone Ethanol Gastric Juice - metabolism Gastric Mucosa - drug effects Gastric Mucosa - metabolism Medical sciences Organometallic Compounds - therapeutic use Pharmacology. Drug treatments Prostaglandins E - metabolism Prostaglandins E, Synthetic - therapeutic use Rats Rats, Inbred Strains Stomach Ulcer - chemically induced Stomach Ulcer - metabolism Stomach Ulcer - prevention & control Sucralfate - therapeutic use
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