Lignocaine kinetics in cardiac patients and aged subjects

1 The pharmacokinetics following long term intravenous infusion of lignocaine to cardiac patients have been examined. 2 Plasma levels and half‐lives of lignocaine and monoethylglycinexylidide (MEGX) showed wide inter‐patient variability. 3 Toxicity reactions to therapy were associated with elevated...

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Veröffentlicht in:	British journal of clinical pharmacology 1977-08, Vol.4 (4), p.439-448
Hauptverfasser:	Nation, RL, Triggs, EJ, Selig, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aging Half-Life Heart Diseases - blood Humans Infusions, Parenteral Injections, Intravenous Kinetics Lidocaine - administration & dosage Lidocaine - adverse effects Lidocaine - blood Male Middle Aged Time Factors
Online-Zugang:	Volltext
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