Molecular beacons with intrinsically fluorescent nucleotides

We report the design, synthesis and characterization of a novel molecular beacon (MB-FB) which uses the fluorescent bases (FB) 2-aminopurine (AP) and pyrrolo-dC (P-dC) as fluorophores. Because the quantum yield of these FB depend on hybridization with complementary target, the fluorescent properties...

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Veröffentlicht in:	Nucleic acids research 2006-01, Vol.34 (6), p.e50-e50
Hauptverfasser:	Martí, Angel A., Jockusch, Steffen, Li, Zengmin, Ju, Jingyue, Turro, Nicholas J.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Aminopurine - chemistry Cytosine - analogs & derivatives Cytosine - chemistry DNA - chemistry Fluorescence Fluorescent Dyes - chemistry Methods Online Nucleic Acid Denaturation Nucleic Acid Hybridization Oligonucleotide Probes - chemistry Spectrometry, Fluorescence Temperature
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