Classical pathway of complement activation in mammalian kidneys

Two monoclonal antibodies (mAb M4d2 and M4d3) specific for the alpha 2-fragment (C4d), and one antibody (mAb M4c3) specific for the gamma-chain of human complement protein C4, have been tested for cross-reactivity against mammalian complement. These mAb have also been found to react with C4 from gui...

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Veröffentlicht in:	Immunology 1993-10, Vol.80 (2), p.162-167
Hauptverfasser:	ZWIRNER, J, FLEBER, E, BURGER, R, BITTER-SUERMANN, D, RIETHMÜLLER, G, FEUCHT, H. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Biological and medical sciences Cattle Complement Complement Activation Complement C2 - deficiency Complement C3 - deficiency Complement C4 - analysis Complement C4 - deficiency Complement C4b Complement Pathway, Classical - immunology Enzyme-Linked Immunosorbent Assay Fundamental and applied biological sciences. Psychology Fundamental immunology Guinea Pigs Humans Immunoenzyme Techniques Immunoglobulin M - analysis Kidney - immunology Macaca mulatta Mammals - immunology Molecular immunology Papio Peptide Fragments - analysis Rabbits Species Specificity
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