Induction of IgE antibodies in mice with recombinant grass pollen antigens

In this study, recombinant Poa pratensis (Poa p) IX allergens were examined for their in vivo allergenicity and antigenicity. Immunization of mice with a fusion protein (FP) comprising beta-galactosidase and recombinant KBG8.3 (rKBG8.3) allergen induced high titres of both IgG and IgE antibodies. By...

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Veröffentlicht in:	Immunology 1992-05, Vol.76 (1), p.158-163
Hauptverfasser:	ZHANG, L, SEHON, A. H, MOHAPATRA, S. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology Animals beta-Galactosidase - immunology Binding, Competitive - immunology Biological and medical sciences Blotting, Western Cross Reactions - immunology Female Fundamental and applied biological sciences. Psychology Fundamental immunology Immediate hypersensitivity. Allergy. Anaphylaxis, etc Immunobiology Immunoglobulin E - biosynthesis Immunoglobulin G - biosynthesis Mice Mice, Inbred Strains Poa pratensis Pollen - immunology Recombinant Proteins - immunology
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