The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis

The MAML (mastermind-like) proteins are a family of three co-transcriptional regulators that are essential for Notch signaling, a pathway critical for cell fate determination. Though the functions of MAML proteins in normal development remain unresolved, their distinct tissue distributions and diffe...

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Veröffentlicht in:	Genes & development 2006-03, Vol.20 (6), p.675-688
Hauptverfasser:	Shen, Huangxuan, McElhinny, Abigail S, Cao, Yang, Gao, Ping, Liu, Jingxuan, Bronson, Roderick, Griffin, James D, Wu, Lizi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence DNA Primers MEF2 Transcription Factors Mice Muscles - embryology Muscular Dystrophies - genetics Myogenic Regulatory Factors - physiology Nuclear Proteins - genetics Nuclear Proteins - physiology Research Paper Transcription Factors - genetics Transcription Factors - physiology Transcription, Genetic - physiology
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