Digestion of native collagen in the gut
The digestion and absorption of collagen, native and artificially cross-linked, has been examined in the rat and the Gaboon viper, by feeding known quantities and measuring the hydroxy-proline content of the faeces and of the contents of the gut at different levels, and comparing with an unabsorbabl...
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| Veröffentlicht in: | Gut 1978-03, Vol.19 (3), p.240-243 |
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| container_title | Gut |
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| creator | Harkness, M L Harkness, R D Venn, M F |
| description | The digestion and absorption of collagen, native and artificially cross-linked, has been examined in the rat and the Gaboon viper, by feeding known quantities and measuring the hydroxy-proline content of the faeces and of the contents of the gut at different levels, and comparing with an unabsorbable marker (polyethylene glycol). Incubation of collagen in vitro with pepsin at 37 degrees C at pH 1.5 followed by trypsin or chymotrypsin converted about 40% into dialysable material. |
| doi_str_mv | 10.1136/gut.19.3.240 |
| format | Article |
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Incubation of collagen in vitro with pepsin at 37 degrees C at pH 1.5 followed by trypsin or chymotrypsin converted about 40% into dialysable material.</description><identifier>ISSN: 0017-5749</identifier><identifier>EISSN: 1468-3288</identifier><identifier>EISSN: 1458-3288</identifier><identifier>DOI: 10.1136/gut.19.3.240</identifier><identifier>PMID: 631645</identifier><identifier>CODEN: GUTTAK</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and British Society of Gastroenterology</publisher><subject>Animals ; Collagen - administration & dosage ; Collagen - metabolism ; Dietary Proteins - administration & dosage ; Digestion ; Digestive System - analysis ; Feces - analysis ; Hydroxyproline - analysis ; Intestinal Absorption ; Male ; Rats ; Snakes - metabolism</subject><ispartof>Gut, 1978-03, Vol.19 (3), p.240-243</ispartof><rights>Copyright BMJ Publishing Group LTD Mar 1978</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b476t-8daf105be8b4a2f9ce66678a1c2734d69cf50d565103f40afd65ce14c87beb23</citedby><cites>FETCH-LOGICAL-b476t-8daf105be8b4a2f9ce66678a1c2734d69cf50d565103f40afd65ce14c87beb23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1411895/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1411895/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27915,27916,53782,53784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/631645$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Harkness, M L</creatorcontrib><creatorcontrib>Harkness, R D</creatorcontrib><creatorcontrib>Venn, M F</creatorcontrib><title>Digestion of native collagen in the gut</title><title>Gut</title><addtitle>Gut</addtitle><description>The digestion and absorption of collagen, native and artificially cross-linked, has been examined in the rat and the Gaboon viper, by feeding known quantities and measuring the hydroxy-proline content of the faeces and of the contents of the gut at different levels, and comparing with an unabsorbable marker (polyethylene glycol). Incubation of collagen in vitro with pepsin at 37 degrees C at pH 1.5 followed by trypsin or chymotrypsin converted about 40% into dialysable material.</description><subject>Animals</subject><subject>Collagen - administration & dosage</subject><subject>Collagen - metabolism</subject><subject>Dietary Proteins - administration & dosage</subject><subject>Digestion</subject><subject>Digestive System - analysis</subject><subject>Feces - analysis</subject><subject>Hydroxyproline - analysis</subject><subject>Intestinal Absorption</subject><subject>Male</subject><subject>Rats</subject><subject>Snakes - metabolism</subject><issn>0017-5749</issn><issn>1468-3288</issn><issn>1458-3288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kM1PFEEUxDsGlRW5efQwCQlcnKXf9OdcSMwCYgKihhDi5aWnp2fpZXd6nZ4h-t_bmyEb9ODpHeqXelVFyDugUwAmj-dDP4VyyqYFpy_IBLjUOSu03iETSkHlQvFyl7yJcUEp1bqE1-SVZCC5mJCjUz93sfehzUKTtab3jy6zYbk0c9dmvs36e5elB2_Jy8Yso9t_unvk5vzsZnaRX15_-jz7eJlXXMk-17VpgIrK6Yqboimtk1IqbcAWivFalrYRtBZSAGUNp6appbAOuNWqclXB9sjJaLseqpWrrWv7zixx3fmV6X5jMB7_Vlp_j_PwiMABdCmSweGTQRd-DqkZrny0LvVpXRgiaqZlWcAGPPgHXISha1M3BKUo5VrCJs-HkbJdiLFzzTYKUNyMj2kbhBIZpvET_v55_C08rp3kfJR97N2vrWq6B5SKKYFfbmd49ePim777_hWvEn808tVq8f_HfwB09ptE</recordid><startdate>19780301</startdate><enddate>19780301</enddate><creator>Harkness, M L</creator><creator>Harkness, R D</creator><creator>Venn, M F</creator><general>BMJ Publishing Group Ltd and British Society of Gastroenterology</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19780301</creationdate><title>Digestion of native collagen in the gut</title><author>Harkness, M L ; Harkness, R D ; Venn, M F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b476t-8daf105be8b4a2f9ce66678a1c2734d69cf50d565103f40afd65ce14c87beb23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Animals</topic><topic>Collagen - administration & dosage</topic><topic>Collagen - metabolism</topic><topic>Dietary Proteins - administration & dosage</topic><topic>Digestion</topic><topic>Digestive System - analysis</topic><topic>Feces - analysis</topic><topic>Hydroxyproline - analysis</topic><topic>Intestinal Absorption</topic><topic>Male</topic><topic>Rats</topic><topic>Snakes - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Harkness, M L</creatorcontrib><creatorcontrib>Harkness, R D</creatorcontrib><creatorcontrib>Venn, M F</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Gut</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Harkness, M L</au><au>Harkness, R D</au><au>Venn, M F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Digestion of native collagen in the gut</atitle><jtitle>Gut</jtitle><addtitle>Gut</addtitle><date>1978-03-01</date><risdate>1978</risdate><volume>19</volume><issue>3</issue><spage>240</spage><epage>243</epage><pages>240-243</pages><issn>0017-5749</issn><eissn>1468-3288</eissn><eissn>1458-3288</eissn><coden>GUTTAK</coden><abstract>The digestion and absorption of collagen, native and artificially cross-linked, has been examined in the rat and the Gaboon viper, by feeding known quantities and measuring the hydroxy-proline content of the faeces and of the contents of the gut at different levels, and comparing with an unabsorbable marker (polyethylene glycol). Incubation of collagen in vitro with pepsin at 37 degrees C at pH 1.5 followed by trypsin or chymotrypsin converted about 40% into dialysable material.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and British Society of Gastroenterology</pub><pmid>631645</pmid><doi>10.1136/gut.19.3.240</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
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| ispartof | Gut, 1978-03, Vol.19 (3), p.240-243 |
| issn | 0017-5749 1468-3288 1458-3288 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1411895 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Animals Collagen - administration & dosage Collagen - metabolism Dietary Proteins - administration & dosage Digestion Digestive System - analysis Feces - analysis Hydroxyproline - analysis Intestinal Absorption Male Rats Snakes - metabolism |
| title | Digestion of native collagen in the gut |
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