Repeated ethanol intoxication induces behavioral sensitization in the absence of a sensitized accumbens dopamine response in C57BL/6J and DBA/2J mice

Repeated exposure to drugs of abuse results in an increased sensitivity to their behavioral effects, a phenomena referred to as behavioral sensitization. It has been suggested that the same neuroadaptations underlying behavioral sensitization contribute to the maintenance and reinstatement of addict...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2006-02, Vol.31 (2), p.396-405
Hauptverfasser:	Zapata, Agustin, Gonzales, Rueben A, Shippenberg, Toni S
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholic Intoxication - etiology Alcoholic Intoxication - physiopathology Animals Behavior, Animal - drug effects Central Nervous System Depressants - administration & dosage Central Nervous System Depressants - blood Dopamine - metabolism Drug Administration Schedule Ethanol - administration & dosage Ethanol - blood Male Mice Mice, Inbred C57BL Mice, Inbred DBA Microdialysis - methods Motor Activity - drug effects Nucleus Accumbens - drug effects Severity of Illness Index Time Factors
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