Human granulocyte chemotactic peptide (IL-8) as a specific neutrophil degranulator: comparison with other monokines

The influence of human monocyte-derived chemotactic peptide (GCP/IL-8) on degranulation of neutrophils was investigated in relation to that of other monokines. GCP/IL-8 promoted a dose-dependent release of lactoferrin from specific granules but had no effect on enzyme release from primary granules....

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Veröffentlicht in:	Immunology 1989-08, Vol.67 (4), p.540-542
Hauptverfasser:	WILLEMS, J, JONIAU, M, CINQUE, S, VAN DAMME, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Biological and medical sciences Biological Factors - pharmacology Chemotactic Factors - pharmacology Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Interleukin-8 L-Lactate Dehydrogenase - metabolism Lactoferrin - metabolism Lymphokines, interleukins ( function, expression) Monokines Neutrophils - drug effects Neutrophils - metabolism Regulatory factors and their cellular receptors
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