Clearance kinetics and tissue distribution of aggregated human serum IgA in rats

In the present study the clearance kinetics and tissue distribution of human polyclonal heat-aggregated serum IgA (AIgA) of different sizes in rats was studied after intravenous administration of 125I-AIgA. The 125I-AIgA of different sizes disappeared from the circulation in a biphasic manner with a...

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Veröffentlicht in:	Immunology 1989-06, Vol.67 (2), p.274-280
Hauptverfasser:	BOGERS, W. M. J. M, GORTER, A, STUURMAN, M. E, VAN ES, L. A, DAHA, M. R
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Fetoproteins - administration & dosage Analysis of the immune response. Humoral and cellular immunity Animals Asialoglycoproteins Binding, Competitive Biological and medical sciences Fetuins Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Immunoglobulin A - pharmacokinetics Injections, Intravenous Liver - metabolism Macromolecular Substances Male Metabolic Clearance Rate - drug effects Molecular Weight Organs and cells involved in the immune response Ovalbumin - administration & dosage Rats Rats, Inbred Strains Sodium Chloride - administration & dosage Tissue Distribution
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