Transcriptional and post-transcriptional mechanisms involved in the differential expression of LPS-induced IL-1 and TNF mRNA

The amplification of cytokine mRNA following incubation of macrophages with inflammatory stimuli and protein synthesis inhibitors has been related to stabilization of labile mRNA species containing the 3'AUUUA consensus sequence. In the present study, cycloheximide-treated lipopolysaccharide (L...

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Veröffentlicht in:Immunology 1991-08, Vol.73 (4), p.460-465
Hauptverfasser: Zuckerman, S H, Evans, G F, Guthrie, L
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Sprache:eng
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