Role of B70/B7-2 in CD4+ T-cell immune responses induced by dendritic cells

Dendritic cells (DC) are potent antigen-presenting cells (APC). However, the molecular basis underlying this activity remains incompletely understood. To address this question, we generated murine monoclonal antibodies (mAb) against human peripheral blood-derived DC. One such antibody, designated IT...

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Veröffentlicht in:	Immunology 1995-07, Vol.85 (3), p.467-474
Hauptverfasser:	Fagnoni, F F, Takamizawa, M, Godfrey, W R, Rivas, A, Azuma, M, Okumura, K, Engleman, E G
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Antibodies, Monoclonal - immunology Antigens - immunology Antigens, CD - immunology B7-2 Antigen CD4-Positive T-Lymphocytes - immunology Cell Division - immunology Dendritic Cells - immunology Gene Products, env - immunology HIV Envelope Protein gp160 Humans Leukocytes, Mononuclear - immunology Lymphocyte Activation - immunology Membrane Glycoproteins - immunology Monocytes - immunology Protein Precursors - immunology Tetanus Toxoid - immunology Tuberculin - immunology
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