The pharmacokinetics and pharmacodynamics of recombinant human erythropoietin in haemodialysis patients

1. The pharmacokinetics of and therapeutic response to recombinant human erythropoietin (rcEPO) were studied in 12 patients under chronic haemodialysis on a thrice weekly intravenous rcEPO treatment scheme. The kinetics of rcEPO were also assessed after a subcutaneous injection during the initial pe...

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Veröffentlicht in:	British journal of clinical pharmacology 1992-12, Vol.34 (6), p.499-508
Hauptverfasser:	BROCKMÖLLER, J, KÖCHLING, J, WEBER, W, LOOBY, M, ROOTS, I, NEUMAYER, H.-H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Erythrocyte Count - drug effects Erythropoietin - blood Erythropoietin - pharmacokinetics Erythropoietin - pharmacology Female Hemoglobins - analysis Hormones. Endocrine system Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments Radioimmunoassay Recombinant Proteins - blood Recombinant Proteins - pharmacokinetics Recombinant Proteins - pharmacology Renal Dialysis Reticulocytes - drug effects
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