Enhanced gastric mucosal bleeding with doses of aspirin used for prophylaxis and its reduction by ranitidine

1. We evaluated injury to the human gastric mucosa caused by low doses of aspirin and its prophylaxis by ranitidine. On two separate occasions, 30 subjects took aspirin 300 mg daily for 12 days either with or without ranitidine 150 mg, 30 min before aspirin. This dose of aspirin caused more than a 5...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	British journal of clinical pharmacology 1989-11, Vol.28 (5), p.581-585
Hauptverfasser:	Kitchingman, GK, Prichard, PJ, Daneshmend, TK, Walt, RP, Hawkey, CJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aspirin - adverse effects Biological and medical sciences Drug toxicity and drugs side effects treatment Female Gastric Acid - metabolism Gastrointestinal Hemorrhage - chemically induced Gastrointestinal Hemorrhage - drug therapy Humans Male Medical sciences Pharmacology. Drug treatments Ranitidine - therapeutic use Toxicity: digestive system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!