Prediction of creatinine clearance from plasma creatinine: comparison of five formulae
1. Glomerular filtration rate is commonly assessed by measurement of endogenous creatinine clearance (CLcr). Several formulae have been described to calculate CLcr from plasma creatinine and we have evaluated the effectiveness of five formulae in 95 healthy subjects (17 F and 78 M, 20‐25 years) and...
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| Veröffentlicht in: | British journal of clinical pharmacology 1989-09, Vol.28 (3), p.275-280 |
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| creator | Robertshaw, M. Lai, KN Swaminathan, R. |
| description | 1. Glomerular filtration rate is commonly assessed by measurement of endogenous creatinine clearance (CLcr). Several formulae have been described to calculate CLcr from plasma creatinine and we have evaluated the effectiveness of five formulae in 95 healthy subjects (17 F and 78 M, 20‐25 years) and in 72 patients attending a renal clinic (48F and 24 M, 14‐69 years). Endogenous CLcr was measured and the CLcr was also estimated by five formulae. 2. In healthy subjects CLcr calculated by the formulae of Cockcroft & Gault (1976) and Mawer et al. (1972) gave higher correlation coefficients than the other three formulae. 3. When all of the subjects with a wide range of CLcr (3.1‐ 164) were considered all formulae gave good correlations, but the formula of Cockcroft & Gault (1976) gave the best estimate. |
| doi_str_mv | 10.1111/j.1365-2125.1989.tb05427.x |
| format | Article |
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Glomerular filtration rate is commonly assessed by measurement of endogenous creatinine clearance (CLcr). Several formulae have been described to calculate CLcr from plasma creatinine and we have evaluated the effectiveness of five formulae in 95 healthy subjects (17 F and 78 M, 20‐25 years) and in 72 patients attending a renal clinic (48F and 24 M, 14‐69 years). Endogenous CLcr was measured and the CLcr was also estimated by five formulae. 2. In healthy subjects CLcr calculated by the formulae of Cockcroft & Gault (1976) and Mawer et al. (1972) gave higher correlation coefficients than the other three formulae. 3. When all of the subjects with a wide range of CLcr (3.1‐ 164) were considered all formulae gave good correlations, but the formula of Cockcroft & Gault (1976) gave the best estimate.</description><identifier>ISSN: 0306-5251</identifier><identifier>EISSN: 1365-2125</identifier><identifier>DOI: 10.1111/j.1365-2125.1989.tb05427.x</identifier><identifier>PMID: 2789921</identifier><identifier>CODEN: BCPHBM</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Anthropology. Demography ; Biological and medical sciences ; Child ; China ; Creatinine - blood ; Creatinine - metabolism ; Creatinine - urine ; Female ; Human physiology applied to population studies and life conditions. Human ecophysiology ; Humans ; Male ; Medical sciences ; Middle Aged ; Models, Biological ; Predictive Value of Tests</subject><ispartof>British journal of clinical pharmacology, 1989-09, Vol.28 (3), p.275-280</ispartof><rights>1989 The British Pharmacological Society</rights><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4877-c75d3b1dadf491046d6ec224774bbf7f23e3b7ec34d69e5d2758be1bb47e55763</citedby><cites>FETCH-LOGICAL-c4877-c75d3b1dadf491046d6ec224774bbf7f23e3b7ec34d69e5d2758be1bb47e55763</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6658251$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2789921$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Robertshaw, M.</creatorcontrib><creatorcontrib>Lai, KN</creatorcontrib><creatorcontrib>Swaminathan, R.</creatorcontrib><title>Prediction of creatinine clearance from plasma creatinine: comparison of five formulae</title><title>British journal of clinical pharmacology</title><addtitle>Br J Clin Pharmacol</addtitle><description>1. Glomerular filtration rate is commonly assessed by measurement of endogenous creatinine clearance (CLcr). Several formulae have been described to calculate CLcr from plasma creatinine and we have evaluated the effectiveness of five formulae in 95 healthy subjects (17 F and 78 M, 20‐25 years) and in 72 patients attending a renal clinic (48F and 24 M, 14‐69 years). Endogenous CLcr was measured and the CLcr was also estimated by five formulae. 2. In healthy subjects CLcr calculated by the formulae of Cockcroft & Gault (1976) and Mawer et al. (1972) gave higher correlation coefficients than the other three formulae. 3. When all of the subjects with a wide range of CLcr (3.1‐ 164) were considered all formulae gave good correlations, but the formula of Cockcroft & Gault (1976) gave the best estimate.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Anthropology. Demography</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>China</subject><subject>Creatinine - blood</subject><subject>Creatinine - metabolism</subject><subject>Creatinine - urine</subject><subject>Female</subject><subject>Human physiology applied to population studies and life conditions. Human ecophysiology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Models, Biological</subject><subject>Predictive Value of Tests</subject><issn>0306-5251</issn><issn>1365-2125</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkV-L1DAUxYMo67j6EYQi4ltr_qfZB0WHXRUW3Af1NSTpjWZomzHprLvf3pYpw_poXhI4v3NzOQehVwQ3ZD5vdw1hUtSUUNEQ3epmclhwqpq7R2hzkh6jDWZY1oIK8hQ9K2WHMWFEijN0RlWrNSUb9OMmQxf9FNNYpVD5DHaKYxyh8j3YbEcPVchpqPa9LYN9AFxUPg17m2M5WkO8ndGUh0Nv4Tl6Emxf4MV6n6PvV5fftp_r66-fvmw_XNeet0rVXomOOdLZLnBNMJedBE8pV4o7F1SgDJhT4BnvpAbRUSVaB8Q5rkAIJdk5enecuz-4AToP45Rtb_Y5Djbfm2Sj-VcZ4y_zM90awpTWXMwD3qwDcvp9gDKZIRYPfW9HSIdilKaUaIVn8OII-pxKyRBOnxBsllbMzizRmyV6s7Ri1lbM3Wx--XDNk3WtYdZfr7ot3vZhyT2WEyalaOcSZ-z9EfsTe7j_jwXMx-3N8mJ_AUeXrF0</recordid><startdate>198909</startdate><enddate>198909</enddate><creator>Robertshaw, M.</creator><creator>Lai, KN</creator><creator>Swaminathan, R.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>198909</creationdate><title>Prediction of creatinine clearance from plasma creatinine: comparison of five formulae</title><author>Robertshaw, M. ; Lai, KN ; Swaminathan, R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4877-c75d3b1dadf491046d6ec224774bbf7f23e3b7ec34d69e5d2758be1bb47e55763</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Anthropology. Demography</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>China</topic><topic>Creatinine - blood</topic><topic>Creatinine - metabolism</topic><topic>Creatinine - urine</topic><topic>Female</topic><topic>Human physiology applied to population studies and life conditions. Human ecophysiology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Models, Biological</topic><topic>Predictive Value of Tests</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Robertshaw, M.</creatorcontrib><creatorcontrib>Lai, KN</creatorcontrib><creatorcontrib>Swaminathan, R.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>British journal of clinical pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Robertshaw, M.</au><au>Lai, KN</au><au>Swaminathan, R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prediction of creatinine clearance from plasma creatinine: comparison of five formulae</atitle><jtitle>British journal of clinical pharmacology</jtitle><addtitle>Br J Clin Pharmacol</addtitle><date>1989-09</date><risdate>1989</risdate><volume>28</volume><issue>3</issue><spage>275</spage><epage>280</epage><pages>275-280</pages><issn>0306-5251</issn><eissn>1365-2125</eissn><coden>BCPHBM</coden><abstract>1. Glomerular filtration rate is commonly assessed by measurement of endogenous creatinine clearance (CLcr). Several formulae have been described to calculate CLcr from plasma creatinine and we have evaluated the effectiveness of five formulae in 95 healthy subjects (17 F and 78 M, 20‐25 years) and in 72 patients attending a renal clinic (48F and 24 M, 14‐69 years). Endogenous CLcr was measured and the CLcr was also estimated by five formulae. 2. In healthy subjects CLcr calculated by the formulae of Cockcroft & Gault (1976) and Mawer et al. (1972) gave higher correlation coefficients than the other three formulae. 3. When all of the subjects with a wide range of CLcr (3.1‐ 164) were considered all formulae gave good correlations, but the formula of Cockcroft & Gault (1976) gave the best estimate.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>2789921</pmid><doi>10.1111/j.1365-2125.1989.tb05427.x</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | British journal of clinical pharmacology, 1989-09, Vol.28 (3), p.275-280 |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Anthropology. Demography Biological and medical sciences Child China Creatinine - blood Creatinine - metabolism Creatinine - urine Female Human physiology applied to population studies and life conditions. Human ecophysiology Humans Male Medical sciences Middle Aged Models, Biological Predictive Value of Tests |
| title | Prediction of creatinine clearance from plasma creatinine: comparison of five formulae |
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