Cyclosporin‐erythromycin interaction in renal transplant patients

1. The interaction between cyclosporin (CyA) and erythromycin was studied in renal transplant patients following oral and intravenous administration of CyA. 2. Blood and plasma CyA concentrations and blood concentrations of metabolite 17 were measured by h.p.l.c. 3. Erythromycin produced almost a tw...

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Veröffentlicht in:	British journal of clinical pharmacology 1989-04, Vol.27 (4), p.475-481
Hauptverfasser:	Gupta, SK, Bakran, A., Johnson, RW, Rowland, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Biological and medical sciences Biological Availability Biotransformation Chromatography, High Pressure Liquid Cyclosporins - metabolism Cyclosporins - pharmacokinetics Drug Interactions Erythromycin - pharmacokinetics Female Humans Immunomodulators Injections, Intravenous Kidney Transplantation Male Medical sciences Pharmacology. Drug treatments Transplantation, Homologous
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