Inhibition of cell mediated cytotoxicity by sulphasalazine: effect of in vivo treatment with 5-aminosalicylic acid and sulphasalazine on in vitro natural killer cell activity

Decreased cell mediated cytotoxicity occurs frequently in inflammatory bowel disease, particularly in patients with active disease. It is not clear, however, whether this decrease is caused by the disease or is a consequence of the medical treatment. In this study we evaluated the effect of in vivo...

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Veröffentlicht in:	Gut 1990-09, Vol.31 (9), p.1030-1032
Hauptverfasser:	Aparicio-Pagés, M N, Verspaget, H W, Hafkenscheid, J C, Crama-Bohbouth, G E, Peña, A S, Weterman, I T, Lamers, H W
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminosalicylic Acids - pharmacology Biological and medical sciences Colitis, Ulcerative - immunology Crohn Disease - immunology Cytotoxicity Tests, Immunologic Cytotoxicity, Immunologic - drug effects Double-Blind Method Drug toxicity and drugs side effects treatment Humans Immunosuppressive Agents - pharmacology Killer Cells, Natural - drug effects Killer Cells, Natural - immunology Medical sciences Mesalamine Miscellaneous (drug allergy, mutagens, teratogens...) Pharmacology. Drug treatments Random Allocation Sulfasalazine - pharmacology
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