Parental Origin–Dependent, Male Offspring–Specific Transmission-Ratio Distortion at Loci on the Human X Chromosome

We have analyzed the transmission of maternal alleles at loci spanning the length of the X chromosome in 47 normal, genetic disease–free families. We found a significant deviation from the expected Mendelian 1:1 ratio of grandpaternal:grandmaternal alleles at loci in Xp11.4-p21.1. The distortion in...

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Veröffentlicht in:	American journal of human genetics 1998-06, Vol.62 (6), p.1493-1499
Hauptverfasser:	Naumova, A.K., Leppert, M., Barker, D.F., Morgan, K., Sapienza, C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Chromosome X Female General aspects. Genetic counseling Genomic Imprinting Humans Male Male offspring Medical genetics Medical sciences Mice Parental origin Recombination, Genetic Transmission-ration distortion X Chromosome
Online-Zugang:	Volltext
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