Location of the lower oesophageal sphincter and the squamous columnar mucosal junction in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis
In this study the location of the lower oesophageal sphincter measured by manometry and the location of the squamous columnar junction measured by endoscopy were determined in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis. No significant differences in the p...
Gespeichert in:
| Veröffentlicht in: | Gut 1993-01, Vol.34 (1), p.21-27 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 27 |
|---|---|
| container_issue | 1 |
| container_start_page | 21 |
| container_title | Gut |
| container_volume | 34 |
| creator | Csendes, A Maluenda, F Braghetto, I Csendes, P Henriquez, A Quesada, M S |
| description | In this study the location of the lower oesophageal sphincter measured by manometry and the location of the squamous columnar junction measured by endoscopy were determined in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis. No significant differences in the prevalence and severity of the heartburn and regurgitation were observed when different degrees of oesophagitis were compared but dysphagia was more common and severe in patients with complicated Barrett's oesophagus (p < 0.001). This group also showed a male predominance and older age compared with other groups. The total length of the oesophagus, measured by the location of the distal end of the lower oesophageal sphincter was similar in all patients; however, the location of the squamous columnar junction extended more proximally and was related to the increasing severity of endoscopic oesophagitis. The manometric defects at the cardia were more frequent in severe oesophagitis (p < 0.001). These results suggest that, during the course of oesophagitis, the squamous columnar junction is displaced proximally. This displacement is limited to the mucosa, however, and does not involve the muscular layer, because the lower oesophageal sphincter undergoes no dislocation. |
| doi_str_mv | 10.1136/gut.34.1.21 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1374094</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3970005431</sourcerecordid><originalsourceid>FETCH-LOGICAL-b4171-cd40cec7c8d1bff07c0663fcd7d8e198da7ce00e736534b4f50187a085c68cb03</originalsourceid><addsrcrecordid>eNp9ks1u1DAUhSMEKkNhxRrJEqgblMGOHduzQUJTaNGMygbK0nIcZ-IhsVPbofSxeEOczij8LFhZ9vl07rnXN8ueI7hECNM3uzEuMVmiZYEeZAtEKM9xwfnDbAEhYnnJyOpx9iSEPYSQ8xU6yU44wQUhdJH93Dolo3EWuAbEVoPO3WoPnA5uaOVOyw6EoTVWxfQqbX3PhJtR9m4MQLlu7K30oB-VC4ndj4mc3IwFCK5Amwxie5dAG73rwr0FYxwMqai2MYBbE1tQm6bRPt1BrXde6zCl0bZ2QbnBqDmOiSY8zR41sgv62fE8zb58eP95fZlvP118XL_b5hVBDOWqJlBpxRSvUdU0kClIKW5UzWqu0YrXkikNoWaYlphUpCkh4kxCXirKVQXxafb24DuMVa9rldJ52YnBm176O-GkEX8r1rRi574LhBmBK5IMzo4G3t2MOkTRm6B010mr0_AEK0tOOJoqvfwH3LvR29ScQIxBSBGlE_X6QCnvQvC6maMgKKY9EGkPBCYCiQIl-sWf6Wf2-PFJf3XUZVCya7y0yoQZI4SzosAJyw-YCVH_mGXpvwnKMCvF1fVaXG6uvl5sNtfi_HfPVb__b75fLyvbng</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1770061660</pqid></control><display><type>article</type><title>Location of the lower oesophageal sphincter and the squamous columnar mucosal junction in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Csendes, A ; Maluenda, F ; Braghetto, I ; Csendes, P ; Henriquez, A ; Quesada, M S</creator><creatorcontrib>Csendes, A ; Maluenda, F ; Braghetto, I ; Csendes, P ; Henriquez, A ; Quesada, M S</creatorcontrib><description>In this study the location of the lower oesophageal sphincter measured by manometry and the location of the squamous columnar junction measured by endoscopy were determined in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis. No significant differences in the prevalence and severity of the heartburn and regurgitation were observed when different degrees of oesophagitis were compared but dysphagia was more common and severe in patients with complicated Barrett's oesophagus (p < 0.001). This group also showed a male predominance and older age compared with other groups. The total length of the oesophagus, measured by the location of the distal end of the lower oesophageal sphincter was similar in all patients; however, the location of the squamous columnar junction extended more proximally and was related to the increasing severity of endoscopic oesophagitis. The manometric defects at the cardia were more frequent in severe oesophagitis (p < 0.001). These results suggest that, during the course of oesophagitis, the squamous columnar junction is displaced proximally. This displacement is limited to the mucosa, however, and does not involve the muscular layer, because the lower oesophageal sphincter undergoes no dislocation.</description><identifier>ISSN: 0017-5749</identifier><identifier>EISSN: 1468-3288</identifier><identifier>EISSN: 1458-3288</identifier><identifier>DOI: 10.1136/gut.34.1.21</identifier><identifier>PMID: 8432446</identifier><identifier>CODEN: GUTTAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and British Society of Gastroenterology</publisher><subject>Biological and medical sciences ; Cardia - pathology ; Esophagitis - pathology ; Esophagitis - physiopathology ; Esophagogastric Junction - pathology ; Esophagogastric Junction - physiopathology ; Esophagoscopy ; Esophagus ; Female ; Gastric Mucosa - pathology ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastroesophageal Reflux - pathology ; Gastroesophageal Reflux - physiopathology ; Gastroscopy ; Humans ; Male ; Manometry ; Medical sciences ; Middle Aged ; Other diseases. Semiology ; Prospective Studies</subject><ispartof>Gut, 1993-01, Vol.34 (1), p.21-27</ispartof><rights>1993 INIST-CNRS</rights><rights>Copyright BMJ Publishing Group LTD Jan 1993</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b4171-cd40cec7c8d1bff07c0663fcd7d8e198da7ce00e736534b4f50187a085c68cb03</citedby><cites>FETCH-LOGICAL-b4171-cd40cec7c8d1bff07c0663fcd7d8e198da7ce00e736534b4f50187a085c68cb03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1374094/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1374094/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,4024,27923,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4487223$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8432446$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Csendes, A</creatorcontrib><creatorcontrib>Maluenda, F</creatorcontrib><creatorcontrib>Braghetto, I</creatorcontrib><creatorcontrib>Csendes, P</creatorcontrib><creatorcontrib>Henriquez, A</creatorcontrib><creatorcontrib>Quesada, M S</creatorcontrib><title>Location of the lower oesophageal sphincter and the squamous columnar mucosal junction in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis</title><title>Gut</title><addtitle>Gut</addtitle><description>In this study the location of the lower oesophageal sphincter measured by manometry and the location of the squamous columnar junction measured by endoscopy were determined in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis. No significant differences in the prevalence and severity of the heartburn and regurgitation were observed when different degrees of oesophagitis were compared but dysphagia was more common and severe in patients with complicated Barrett's oesophagus (p < 0.001). This group also showed a male predominance and older age compared with other groups. The total length of the oesophagus, measured by the location of the distal end of the lower oesophageal sphincter was similar in all patients; however, the location of the squamous columnar junction extended more proximally and was related to the increasing severity of endoscopic oesophagitis. The manometric defects at the cardia were more frequent in severe oesophagitis (p < 0.001). These results suggest that, during the course of oesophagitis, the squamous columnar junction is displaced proximally. This displacement is limited to the mucosa, however, and does not involve the muscular layer, because the lower oesophageal sphincter undergoes no dislocation.</description><subject>Biological and medical sciences</subject><subject>Cardia - pathology</subject><subject>Esophagitis - pathology</subject><subject>Esophagitis - physiopathology</subject><subject>Esophagogastric Junction - pathology</subject><subject>Esophagogastric Junction - physiopathology</subject><subject>Esophagoscopy</subject><subject>Esophagus</subject><subject>Female</subject><subject>Gastric Mucosa - pathology</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastroesophageal Reflux - pathology</subject><subject>Gastroesophageal Reflux - physiopathology</subject><subject>Gastroscopy</subject><subject>Humans</subject><subject>Male</subject><subject>Manometry</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Other diseases. Semiology</subject><subject>Prospective Studies</subject><issn>0017-5749</issn><issn>1468-3288</issn><issn>1458-3288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9ks1u1DAUhSMEKkNhxRrJEqgblMGOHduzQUJTaNGMygbK0nIcZ-IhsVPbofSxeEOczij8LFhZ9vl07rnXN8ueI7hECNM3uzEuMVmiZYEeZAtEKM9xwfnDbAEhYnnJyOpx9iSEPYSQ8xU6yU44wQUhdJH93Dolo3EWuAbEVoPO3WoPnA5uaOVOyw6EoTVWxfQqbX3PhJtR9m4MQLlu7K30oB-VC4ndj4mc3IwFCK5Amwxie5dAG73rwr0FYxwMqai2MYBbE1tQm6bRPt1BrXde6zCl0bZ2QbnBqDmOiSY8zR41sgv62fE8zb58eP95fZlvP118XL_b5hVBDOWqJlBpxRSvUdU0kClIKW5UzWqu0YrXkikNoWaYlphUpCkh4kxCXirKVQXxafb24DuMVa9rldJ52YnBm176O-GkEX8r1rRi574LhBmBK5IMzo4G3t2MOkTRm6B010mr0_AEK0tOOJoqvfwH3LvR29ScQIxBSBGlE_X6QCnvQvC6maMgKKY9EGkPBCYCiQIl-sWf6Wf2-PFJf3XUZVCya7y0yoQZI4SzosAJyw-YCVH_mGXpvwnKMCvF1fVaXG6uvl5sNtfi_HfPVb__b75fLyvbng</recordid><startdate>199301</startdate><enddate>199301</enddate><creator>Csendes, A</creator><creator>Maluenda, F</creator><creator>Braghetto, I</creator><creator>Csendes, P</creator><creator>Henriquez, A</creator><creator>Quesada, M S</creator><general>BMJ Publishing Group Ltd and British Society of Gastroenterology</general><general>BMJ</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>199301</creationdate><title>Location of the lower oesophageal sphincter and the squamous columnar mucosal junction in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis</title><author>Csendes, A ; Maluenda, F ; Braghetto, I ; Csendes, P ; Henriquez, A ; Quesada, M S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b4171-cd40cec7c8d1bff07c0663fcd7d8e198da7ce00e736534b4f50187a085c68cb03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>Biological and medical sciences</topic><topic>Cardia - pathology</topic><topic>Esophagitis - pathology</topic><topic>Esophagitis - physiopathology</topic><topic>Esophagogastric Junction - pathology</topic><topic>Esophagogastric Junction - physiopathology</topic><topic>Esophagoscopy</topic><topic>Esophagus</topic><topic>Female</topic><topic>Gastric Mucosa - pathology</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Gastroesophageal Reflux - pathology</topic><topic>Gastroesophageal Reflux - physiopathology</topic><topic>Gastroscopy</topic><topic>Humans</topic><topic>Male</topic><topic>Manometry</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Other diseases. Semiology</topic><topic>Prospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Csendes, A</creatorcontrib><creatorcontrib>Maluenda, F</creatorcontrib><creatorcontrib>Braghetto, I</creatorcontrib><creatorcontrib>Csendes, P</creatorcontrib><creatorcontrib>Henriquez, A</creatorcontrib><creatorcontrib>Quesada, M S</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Gut</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Csendes, A</au><au>Maluenda, F</au><au>Braghetto, I</au><au>Csendes, P</au><au>Henriquez, A</au><au>Quesada, M S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Location of the lower oesophageal sphincter and the squamous columnar mucosal junction in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis</atitle><jtitle>Gut</jtitle><addtitle>Gut</addtitle><date>1993-01</date><risdate>1993</risdate><volume>34</volume><issue>1</issue><spage>21</spage><epage>27</epage><pages>21-27</pages><issn>0017-5749</issn><eissn>1468-3288</eissn><eissn>1458-3288</eissn><coden>GUTTAK</coden><abstract>In this study the location of the lower oesophageal sphincter measured by manometry and the location of the squamous columnar junction measured by endoscopy were determined in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis. No significant differences in the prevalence and severity of the heartburn and regurgitation were observed when different degrees of oesophagitis were compared but dysphagia was more common and severe in patients with complicated Barrett's oesophagus (p < 0.001). This group also showed a male predominance and older age compared with other groups. The total length of the oesophagus, measured by the location of the distal end of the lower oesophageal sphincter was similar in all patients; however, the location of the squamous columnar junction extended more proximally and was related to the increasing severity of endoscopic oesophagitis. The manometric defects at the cardia were more frequent in severe oesophagitis (p < 0.001). These results suggest that, during the course of oesophagitis, the squamous columnar junction is displaced proximally. This displacement is limited to the mucosa, however, and does not involve the muscular layer, because the lower oesophageal sphincter undergoes no dislocation.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and British Society of Gastroenterology</pub><pmid>8432446</pmid><doi>10.1136/gut.34.1.21</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0017-5749 |
| ispartof | Gut, 1993-01, Vol.34 (1), p.21-27 |
| issn | 0017-5749 1468-3288 1458-3288 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1374094 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Biological and medical sciences Cardia - pathology Esophagitis - pathology Esophagitis - physiopathology Esophagogastric Junction - pathology Esophagogastric Junction - physiopathology Esophagoscopy Esophagus Female Gastric Mucosa - pathology Gastroenterology. Liver. Pancreas. Abdomen Gastroesophageal Reflux - pathology Gastroesophageal Reflux - physiopathology Gastroscopy Humans Male Manometry Medical sciences Middle Aged Other diseases. Semiology Prospective Studies |
| title | Location of the lower oesophageal sphincter and the squamous columnar mucosal junction in 109 healthy controls and 778 patients with different degrees of endoscopic oesophagitis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T23%3A57%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Location%20of%20the%20lower%20oesophageal%20sphincter%20and%20the%20squamous%20columnar%20mucosal%20junction%20in%20109%20healthy%20controls%20and%20778%20patients%20with%20different%20degrees%20of%20endoscopic%20oesophagitis&rft.jtitle=Gut&rft.au=Csendes,%20A&rft.date=1993-01&rft.volume=34&rft.issue=1&rft.spage=21&rft.epage=27&rft.pages=21-27&rft.issn=0017-5749&rft.eissn=1468-3288&rft.coden=GUTTAK&rft_id=info:doi/10.1136/gut.34.1.21&rft_dat=%3Cproquest_pubme%3E3970005431%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1770061660&rft_id=info:pmid/8432446&rfr_iscdi=true |