Mutational analysis of the protein subunits of the signal recognition particle Alu-domain

Two polypeptides of the murine signal recognition particle (SRP), SRP9 and SRP14, bind exclusively as a heterodimer to SRP RNA and their presence is required for elongation arrest activity of the particle. SRP9/14 also constitute a subunit of small cytoplasmic Alu RNPs. To identify RNA-binding deter...

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Veröffentlicht in:RNA (Cambridge) 1997-07, Vol.3 (7), p.748-763
Hauptverfasser: Bui, N, Wolff, N, Cusack, S, Strub, K
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Sprache:eng
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