Cis-acting elements distinct from the 5' splice site promote U1-independent pre-mRNA splicing

We have identified a class of pre-mRNAs that are spliced in HeLa extracts depleted for U1 snRNP (delta U1 extracts). Previously, we described pre-mRNAs that can be spliced in delta U1 extracts only when high concentrations of SR splicing factors are added. In contrast, the substrates characterized h...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	RNA (Cambridge) 1996-07, Vol.2 (7), p.664-673
Hauptverfasser:	Crispino, J D, Mermoud, J E, Lamond, A I, Sharp, P A
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Cell Extracts Drosophila Fushi Tarazu Transcription Factors Globins - genetics HeLa Cells Homeodomain Proteins - genetics Humans Molecular Sequence Data Recombinant Proteins - genetics Regulatory Sequences, Nucleic Acid Ribonucleoprotein, U1 Small Nuclear - genetics RNA Precursors - genetics RNA Splicing RNA, Messenger - genetics RNA, Small Nuclear RNA-Binding Proteins - genetics Substrate Specificity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!