Lack of a pharmacokinetic interaction between phenobarbitone and gabapentin

Twelve subjects received a single oral dose (300 mg) of gabapentin and serial blood and urine samples were collected for drug measurements. Oral phenobarbitone (30‐90 mg/day) was then administered to steady‐ state, and the gabapentin single dose study was repeated on day 42. Gabapentin was administe...

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