Pharmacokinetics of zidovudine and dideoxyinosine alone and in combination in patients with the acquired immunodeficiency syndrome

1. Zidovudine (ZDV) has proved unsuccessful in controlling disease progression over extended periods of time in patients with AIDS. Combination of ZDV with another reverse transcriptase inhibitor, dideoxyinosine (ddI) may improve the duration of effectiveness of antiretroviral therapy. The aim of th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	British journal of clinical pharmacology 1994-05, Vol.37 (5), p.421-426
Hauptverfasser:	Barry, M., Howe, JL, Ormesher, S., Back, DJ, Breckenridge, AM, Bergin, C., Mulcahy, F., Beeching, N., Nye, F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Acquired Immunodeficiency Syndrome - drug therapy Acquired Immunodeficiency Syndrome - metabolism Administration, Oral Adult Antibiotics. Antiinfectious agents. Antiparasitic agents antiretroviral therapy Antiviral agents Biological and medical sciences Chromatography, High Pressure Liquid Didanosine - administration & dosage Didanosine - pharmacokinetics Didanosine - therapeutic use Drug interaction Drug Interactions Drug Therapy, Combination Half-Life Humans Immunodeficiency Kidney Male Medical sciences Metabolic Clearance Rate Middle Aged Pharmacokinetics Pharmacology. Drug treatments RNA-directed DNA polymerase Zidovudine Zidovudine - administration & dosage Zidovudine - analogs & derivatives Zidovudine - blood Zidovudine - pharmacokinetics Zidovudine - therapeutic use Zidovudine - urine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!