Immunolocalization of protease‐activated receptor‐2 in skin: receptor activation stimulates interleukin‐8 secretion by keratinocytes in vitro

The protease‐activated receptor‐2 (PAR‐2) is a seven transmembrane domain receptor related to the thrombin receptor, which is activated in vitro by cleavage by trypsin. Affinity‐purified rabbit IgG raised against a peptide corresponding to the trypsin cleavage site of PAR‐2 was used for an immunohis...

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