Human telomeric DNA: G‐quadruplex, i‐motif and Watson–Crick double helix

Human telomeric DNA composed of (TTAGGG/CCCTAA)n repeats may form a classical Watson–Crick double helix. Each individual strand is also prone to quadruplex formation: the G‐rich strand may adopt a G‐quadruplex conformation involving G‐quartets whereas the C‐rich strand may fold into an i‐motif based...

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