The efficacy of polymerized pyridoxylated hemoglobin solution as an O2 carrier

A polymerized pyridoxylated hemoglobin solution (Poly SFH-P) has been prepared with a normal [Hb] of 14 g/dL, a normal COP of 20 to 25 torr, a P50 of 16 to 20 torr, and a plasma T1/2 of 40 to 46 hours. Animals underwent a total exchange transfusion with Poly SFH-P to assess its ability to support he...

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Veröffentlicht in:	Annals of surgery 1990-04, Vol.211 (4), p.394-398
Hauptverfasser:	Gould, S A, Sehgal, L R, Rosen, A L, Sehgal, H L, Moss, G S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood Substitutes Exchange Transfusion, Whole Blood Hematocrit Hemodynamics - physiology Hemoglobins Oxygen Consumption - physiology Papio Pyridoxal Phosphate - analogs & derivatives
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