A long-term randomized prospective trial of the Nissen procedure versus a modified Toupet technique
Thirty-one patients about to undergo surgery for gastroesophageal reflux were randomized into either a Nissen fundoplication group (12) or a modified Toupet semifundoplication group (19). All patients were followed on a long-term basis for 5 years with a standard questionnaire, endoscopy, and manome...
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Veröffentlicht in: | Annals of surgery 1989-12, Vol.210 (6), p.719-724 |
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description | Thirty-one patients about to undergo surgery for gastroesophageal reflux were randomized into either a Nissen fundoplication group (12) or a modified Toupet semifundoplication group (19). All patients were followed on a long-term basis for 5 years with a standard questionnaire, endoscopy, and manometry. Ninety-five percent of the patients in the modified Toupet group had good or excellent results versus 67% for the Nissen group. However both procedures are effective in curtailing esophagitis with an improvement of the endoscopic grading in the Nissen group by 91% and 89% in the group undergoing the modified Toupet procedure. A significant improvement in symptoms (acid regurgitation, heartburn, retrosternal pain) was noted in both groups, except for dysphagia in the Nissen group. Three patients with a Nissen fundoplication had a slipped Nissen requiring reoperation and two had gas-bloat syndrome. These specific complications of the Nissen procedure were not found in the modified Toupet group. |
doi_str_mv | 10.1097/00000658-198912000-00005 |
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Three patients with a Nissen fundoplication had a slipped Nissen requiring reoperation and two had gas-bloat syndrome. These specific complications of the Nissen procedure were not found in the modified Toupet group.</description><identifier>ISSN: 0003-4932</identifier><identifier>EISSN: 1528-1140</identifier><identifier>DOI: 10.1097/00000658-198912000-00005</identifier><identifier>PMID: 2686567</identifier><identifier>CODEN: ANSUA5</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott</publisher><subject>Adult ; Aged ; Biological and medical sciences ; Esophagus ; Female ; Gastric Fundus - surgery ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastroesophageal Reflux - surgery ; Humans ; Male ; Medical sciences ; Methods ; Middle Aged ; Other diseases. 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B. A</creatorcontrib><creatorcontrib>SILANDER, T</creatorcontrib><title>A long-term randomized prospective trial of the Nissen procedure versus a modified Toupet technique</title><title>Annals of surgery</title><addtitle>Ann Surg</addtitle><description>Thirty-one patients about to undergo surgery for gastroesophageal reflux were randomized into either a Nissen fundoplication group (12) or a modified Toupet semifundoplication group (19). All patients were followed on a long-term basis for 5 years with a standard questionnaire, endoscopy, and manometry. Ninety-five percent of the patients in the modified Toupet group had good or excellent results versus 67% for the Nissen group. However both procedures are effective in curtailing esophagitis with an improvement of the endoscopic grading in the Nissen group by 91% and 89% in the group undergoing the modified Toupet procedure. A significant improvement in symptoms (acid regurgitation, heartburn, retrosternal pain) was noted in both groups, except for dysphagia in the Nissen group. Three patients with a Nissen fundoplication had a slipped Nissen requiring reoperation and two had gas-bloat syndrome. These specific complications of the Nissen procedure were not found in the modified Toupet group.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Esophagus</subject><subject>Female</subject><subject>Gastric Fundus - surgery</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastroesophageal Reflux - surgery</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methods</subject><subject>Middle Aged</subject><subject>Other diseases. Semiology</subject><subject>Prospective Studies</subject><issn>0003-4932</issn><issn>1528-1140</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUcuOFCEUJUYztqOfYMLCuCsFiufGZDLxlUx0M64JA5dpTFVRAtWJfr2003aUDeG8uHAQwpS8ocSot-S4pNADNdpQ1g_DERGP0I4K1mHKyWO069A4cDOyp-hZrd8JoVwTdYEumNRSSLVD_gpPebkfGpQZF7eEPKdfEPBacl3Bt3QA3EpyE84Rtz3gL6lWWI68h7AVwAcodavY4TmHFFP33uZthYYb-P2SfmzwHD2Jbqrw4rRfom8f3t9efxpuvn78fH11M3jOeRticAK04E4qcDoaJhX1MowUeARC6agcRM8NKA5OBBFAEydlf_2dB0bMeInePeSu290MwcPSipvsWtLsyk-bXbL_M0va2_t8sHQUSkvWA16fAkruc9dm51Q9TJNbIG_VKjMKyajqQv0g9P2baoF4voQSeyzI_i3Ingv6A4luffnvkGfjqZHOvzrxrno3xd6JT_Usk5IZJuj4G0KAm1s</recordid><startdate>19891201</startdate><enddate>19891201</enddate><creator>THOR, K. B. A</creator><creator>SILANDER, T</creator><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19891201</creationdate><title>A long-term randomized prospective trial of the Nissen procedure versus a modified Toupet technique</title><author>THOR, K. B. A ; SILANDER, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-fda5e854a67ea8f92671c6d31e4fe01137aefc49e74ea5d5de80a66120bce2093</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Esophagus</topic><topic>Female</topic><topic>Gastric Fundus - surgery</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Gastroesophageal Reflux - surgery</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Methods</topic><topic>Middle Aged</topic><topic>Other diseases. Semiology</topic><topic>Prospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>THOR, K. B. A</creatorcontrib><creatorcontrib>SILANDER, T</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>THOR, K. B. A</au><au>SILANDER, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A long-term randomized prospective trial of the Nissen procedure versus a modified Toupet technique</atitle><jtitle>Annals of surgery</jtitle><addtitle>Ann Surg</addtitle><date>1989-12-01</date><risdate>1989</risdate><volume>210</volume><issue>6</issue><spage>719</spage><epage>724</epage><pages>719-724</pages><issn>0003-4932</issn><eissn>1528-1140</eissn><coden>ANSUA5</coden><abstract>Thirty-one patients about to undergo surgery for gastroesophageal reflux were randomized into either a Nissen fundoplication group (12) or a modified Toupet semifundoplication group (19). All patients were followed on a long-term basis for 5 years with a standard questionnaire, endoscopy, and manometry. Ninety-five percent of the patients in the modified Toupet group had good or excellent results versus 67% for the Nissen group. However both procedures are effective in curtailing esophagitis with an improvement of the endoscopic grading in the Nissen group by 91% and 89% in the group undergoing the modified Toupet procedure. A significant improvement in symptoms (acid regurgitation, heartburn, retrosternal pain) was noted in both groups, except for dysphagia in the Nissen group. Three patients with a Nissen fundoplication had a slipped Nissen requiring reoperation and two had gas-bloat syndrome. These specific complications of the Nissen procedure were not found in the modified Toupet group.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>2686567</pmid><doi>10.1097/00000658-198912000-00005</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Journals@Ovid Complete |
subjects | Adult Aged Biological and medical sciences Esophagus Female Gastric Fundus - surgery Gastroenterology. Liver. Pancreas. Abdomen Gastroesophageal Reflux - surgery Humans Male Medical sciences Methods Middle Aged Other diseases. Semiology Prospective Studies |
title | A long-term randomized prospective trial of the Nissen procedure versus a modified Toupet technique |
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