A cell‐autonomous requirement for the cell cycle regulatory protein, Rb, in neuronal migration

Precise cell cycle regulation is critical for nervous system development. To assess the role of the cell cycle regulator, retinoblastoma (Rb) protein, in forebrain development, we studied mice with telencephalon‐specific Rb deletions. We examined the role of Rb in neuronal specification and migratio...

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Veröffentlicht in:	The EMBO journal 2005-12, Vol.24 (24), p.4381-4391
Hauptverfasser:	Ferguson, Kerry L, McClellan, Kelly A, Vanderluit, Jacqueline L, McIntosh, William C, Schuurmans, Carol, Polleux, Franck, Slack, Ruth S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Body Patterning Calbindins Cell Cycle Cell Differentiation Cell Lineage Cell Movement Cell Survival Coculture Techniques EMBO11 EMBO27 Embryo, Mammalian - metabolism Gene Expression Regulation, Developmental Genotype Homeodomain Proteins - metabolism Immunohistochemistry In Situ Hybridization LIM-Homeodomain Proteins Mice Models, Anatomic Mutants Mutation Nerve Tissue Proteins - metabolism neurogenesis neuronal differentiation Neurons - metabolism retinoblastoma Retinoblastoma - metabolism Retinoblastoma Protein - metabolism S100 Calcium Binding Protein G - metabolism Stem Cells - metabolism tangential migration Telencephalon - metabolism Time Factors Transcription Factors
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