Tandem chimerism as a means to increase protein complexity in the human genome

The "one-gene, one-protein" rule, coined by Beadle and Tatum, has been fundamental to molecular biology. The rule implies that the genetic complexity of an organism depends essentially on its gene number. The discovery, however, that alternative gene splicing and transcription are widespre...

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Veröffentlicht in:	Genome Research 2006-01, Vol.16 (1), p.37-44
Hauptverfasser:	Parra, Genís, Reymond, Alexandre, Dabbouseh, Noura, Dermitzakis, Emmanouil T, Castelo, Robert, Thomson, Timothy M, Antonarakis, Stylianos E, Guigó, Roderic
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene Fusion - genetics Genome, Human - genetics Humans Letters RNA Splicing - genetics Transcription, Genetic - genetics
Online-Zugang:	Volltext
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