SitesBase: a database for structure-based protein-ligand binding site comparisons
There are many components which govern the function of a protein within a cell. Here, we focus on the molecular recognition of small molecules and the prediction of common recognition by similarity between protein-ligand binding sites. SitesBase is an easily accessible database which is simple to us...
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| Veröffentlicht in: | Nucleic acids research 2006-01, Vol.34 (1), p.D231-D234 |
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| container_end_page | D234 |
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| container_title | Nucleic acids research |
| container_volume | 34 |
| creator | Gold, Nicola D Jackson, Richard M |
| description | There are many components which govern the function of a protein within a cell. Here, we focus on the molecular recognition of small molecules and the prediction of common recognition by similarity between protein-ligand binding sites. SitesBase is an easily accessible database which is simple to use and holds information about structural similarities between known ligand binding sites found in the Protein Data Bank. These similarities are presented to the wider community enabling full analysis of molecular recognition and potentially protein structure-function relationships. SitesBase is accessible at http://www.bioinformatics.leeds.ac.uk/sb. |
| doi_str_mv | 10.1093/nar/gkj062 |
| format | Article |
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Acids Res</addtitle><date>2006-01-01</date><risdate>2006</risdate><volume>34</volume><issue>1</issue><spage>D231</spage><epage>D234</epage><pages>D231-D234</pages><issn>0305-1048</issn><eissn>1362-4962</eissn><coden>NARHAD</coden><abstract>There are many components which govern the function of a protein within a cell. Here, we focus on the molecular recognition of small molecules and the prediction of common recognition by similarity between protein-ligand binding sites. SitesBase is an easily accessible database which is simple to use and holds information about structural similarities between known ligand binding sites found in the Protein Data Bank. These similarities are presented to the wider community enabling full analysis of molecular recognition and potentially protein structure-function relationships. 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| identifier | ISSN: 0305-1048 |
| ispartof | Nucleic acids research, 2006-01, Vol.34 (1), p.D231-D234 |
| issn | 0305-1048 1362-4962 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_1347425 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Oxford Journals Open Access Collection; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Binding Sites bioinformatics Databases, Protein Internet Internet resource Ligands Models, Molecular prediction protein structure Proteins - chemistry Proteins - metabolism User-Computer Interface |
| title | SitesBase: a database for structure-based protein-ligand binding site comparisons |
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