Agonist-induced regulation of mitochondrial and endoplasmic reticulum motility

Using fluorescently tagged markers for organelles in conjunction with confocal microscopy, we have studied the effects of agonist-induced Ca2+ signals on the motility of mitochondria and the ER (endoplasmic reticulum). We observed that the muscarinic agonist carbachol produced a rapid, simultaneous...

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Veröffentlicht in:	Biochemical journal 2005-12, Vol.392 (Pt 2), p.291-297
Hauptverfasser:	Brough, David, Schell, Michael J, Irvine, Robin F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Biological Transport, Active - drug effects Calcium - metabolism Calcium Signaling - drug effects Calcium Signaling - physiology Carbachol - pharmacology Cell Line Cholinergic Agonists - pharmacology Endoplasmic Reticulum - drug effects Endoplasmic Reticulum - physiology Humans Mitochondria - drug effects Mitochondria - physiology Movement - drug effects
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