Ultrafine Particles Cross Cellular Membranes by Nonphagocytic Mechanisms in Lungs and in Cultured Cells

High concentrations of airborne particles have been associated with increased pulmonary and cardiovascular mortality, with indications of a specific toxicologic role for ultrafine particles (UFPs; particles < 0.1 μm). Within hours after the respiratory system is exposed to UFPs, the UFPs may appe...

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Veröffentlicht in:	Environmental health perspectives 2005-11, Vol.113 (11), p.1555-1560
Hauptverfasser:	Geiser, Marianne, Rothen-Rutishauser, Barbara, Kapp, Nadine, Schürch, Samuel, Kreyling, Wolfgang, Schulz, Holger, Semmler, Manuela, Hof, Vinzenz Im, Heyder, Joachim, Gehr, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerosols Air Pollutants - pharmacokinetics Animals Cell membranes Cells, Cultured Dust Endocytosis Endothelial cells Epithelium Erythrocytes Erythrocytes - metabolism Humans Inhalation Lung - metabolism Lung - ultrastructure Lungs Macrophages Macrophages, Alveolar - metabolism Male Microscopy, Confocal Microscopy, Electron, Transmission Microspheres Particle Size Phagocytes Polystyrenes - administration & dosage Rats Rats, Inbred WKY Swine Titanium - administration & dosage
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