The Effects of Gramicidin on the Structure of Phospholipid Assemblies

Gramicidin is an antibiotic peptide that can be incorporated into the monolayers of cell membranes. Dimerization through hydrogen bonding between gramicidin monomers in opposing leaflets of the membrane results in the formation of an iontophoretic channel. Surrounding phospholipids influence the gat...

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Veröffentlicht in:	Biophysical journal 2003-09, Vol.85 (3), p.1702-1712
Hauptverfasser:	Szule, J.A., Rand, R.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Antibiotics Biophysical Phenomena Biophysics Dimerization Fluid dynamics Gramicidin - chemistry Gramicidin - pharmacology Hydrogen Bonding Lipid Bilayers Lipids Membranes Models, Statistical Osmosis Peptides Phosphatidylcholines - chemistry Phosphatidylethanolamines - chemistry Phospholipids - chemistry Temperature Water - chemistry X-Ray Diffraction
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