Force Spectroscopy of the Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction

Interactions between leukocyte function-associated antigen-1 (LFA-1) with its cognate ligand, intercellular adhesion molecule-1 (ICAM-1) play a crucial role in leukocyte adhesion. Because the cell and its adhesive components are subject to external perturbation from the surrounding flow of blood, it...

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Veröffentlicht in:	Biophysical journal 2002-10, Vol.83 (4), p.2270-2279
Hauptverfasser:	Zhang, Xiaohui, Wojcikiewicz, Ewa, Moy, Vincent T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cations Cell Adhesion Fibroblasts - metabolism Humans Intercellular Adhesion Molecule-1 - metabolism Kinetics Leukocytes Lymphocyte Function-Associated Antigen-1 - metabolism Mice Microscopy, Atomic Force - methods Models, Statistical Molecules Protein Binding Scientific imaging Thermodynamics Tumor Cells, Cultured
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