Applying Hidden Markov Models to the Analysis of Single Ion Channel Activity

Hidden Markov models have recently been used to model single ion channel currents as recorded with the patch clamp technique from cell membranes. The estimation of hidden Markov models parameters using the forward-backward and Baum-Welch algorithms can be performed at signal to noise ratios that are...

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Veröffentlicht in:	Biophysical journal 2002-04, Vol.82 (4), p.1930-1942
Hauptverfasser:	Venkataramanan, L., Sigworth, F.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biophysics Biophysics - methods Ions Ions - chemistry Kinetics Likelihood Functions Markov analysis Markov Chains Membranes Models, Statistical Models, Theoretical Patch-Clamp Techniques Time Factors
Online-Zugang:	Volltext
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