Entrapment and Condensation of DNA in Neutral Reverse Micelles

DNA condensation and compaction is induced by a variety of condensing agents such as polycations. The present study analyzed the structure of plasmid DNA (DNA) in the small inner space of reverse micelles formed from nonionic surfactants (isotropic phase). Spectroscopic studies indicated that DNA wa...

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Veröffentlicht in:	Biophysical journal 2002-03, Vol.82 (3), p.1570-1579
Hauptverfasser:	Budker, Vladimir G., Slattum, Paul M., Monahan, Sean D., Wolff, Jon A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biophysics Circular Dichroism Condensation Cross-Linking Reagents - pharmacology Cysteine - chemistry Deoxyribonucleic acid DNA DNA - chemistry DNA, Complementary - metabolism Electrophoresis, Agar Gel Ethidium - pharmacology Intercalating Agents - pharmacology Micelles Microscopy, Atomic Force Microscopy, Electron Spectrophotometry Ultraviolet Rays Water - chemistry
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