Radiation Inactivation of Ribonucleotide Reductase, an Enzyme with a Stable Free Radical

Herpes simplex virus ribonucleotide reductase (RR) is a tetrameric enzyme composed of two homodimers of large R1 and small R2 subunits with a tyrosyl free radical located on the small subunit. Irradiation of the holoenzyme yielded simple exponential decay curves and an estimated functional target si...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biophysical journal 2000-10, Vol.79 (4), p.2155-2161
Hauptverfasser:	Bolger, Gordon, Liuzzi, Michel, Krogsrud, Richard, Scouten, Erika, McCollum, Robert, Welchner, Ewald, Kempner, Ellis
Format:	Artikel
Sprache:	eng
Schlagworte:	Biophysical Phenomena Biophysics Deoxyribonucleic acid DNA Energy Transfer Enzymes Free Radicals - chemistry Herpes viruses Herpesvirus 1, Human - enzymology Holoenzymes - chemistry Holoenzymes - radiation effects Molecular Weight Protein Subunits Radiation Recombinant Proteins - antagonists & inhibitors Recombinant Proteins - chemistry Recombinant Proteins - radiation effects Ribonucleic acid Ribonucleotide Reductases - antagonists & inhibitors Ribonucleotide Reductases - chemistry Ribonucleotide Reductases - radiation effects RNA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!