Cross-Linking of Cell Surface Receptors Enhances Cooperativity of Molecular Adhesion

Cooperativity of molecular adhesion has been proposed as a mechanism for enhanced binding strength of adhesion molecules on the cell surface. Direct evidence for its mechanism, however, has been lacking until now. Atomic force microscopy (AFM) was used to measure the adhesive strength between concan...

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Veröffentlicht in:	Biophysical journal 2000-06, Vol.78 (6), p.2814-2820
Hauptverfasser:	Chen, Aileen, Moy, Vincent T.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Cell Adhesion - drug effects Cell Adhesion - physiology Cellular biology Concanavalin A - metabolism Cross-Linking Reagents Glutaral - pharmacology Mice Microscopy, Atomic Force Models, Biological Receptors, Cell Surface - physiology Receptors, Concanavalin A - drug effects Receptors, Concanavalin A - physiology Succinimides - pharmacology
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