Multivariate Analysis of Glycosylated Haemoglobin in Insulin-Treated Diabetics
Glycosylated haemoglobin (HbAl), as an assessment of overall control, was estimated in 858 insulin-treated diabetics attending for changeover to U100 insulin in North East Wales. Details of age, sex, duration of diabetes, insulin regimen and monitoring method were recorded. Multivariate analysis rev...
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| Veröffentlicht in: | Journal of the Royal Society of Medicine 1985-07, Vol.78 (7), p.549-551 |
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| container_title | Journal of the Royal Society of Medicine |
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| creator | Child, D F Wood, Jane Hudson, P R Williams, C P Roberts, D R Smith, C |
| description | Glycosylated haemoglobin (HbAl), as an assessment of overall control, was estimated in 858 insulin-treated diabetics attending for changeover to U100 insulin in North East Wales. Details of age, sex, duration of diabetes, insulin regimen and monitoring method were recorded. Multivariate analysis revealed lower HbAl in patients receiving twice-daily (mean 11.01) as compared with once-daily insulin (11.42, P=0.011), but no difference was found between urine and blood glucose testers when other variables were taken into consideration. HbAl was lower in men (mean 10.94) compared with women (mean 11.39, P=0.004) and there was a positive correlation of HbAl in men with age (P= 0.046) and in women with duration of disease (P=0.005). |
| doi_str_mv | 10.1177/014107688507800706 |
| format | Article |
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Details of age, sex, duration of diabetes, insulin regimen and monitoring method were recorded. Multivariate analysis revealed lower HbAl in patients receiving twice-daily (mean 11.01) as compared with once-daily insulin (11.42, P=0.011), but no difference was found between urine and blood glucose testers when other variables were taken into consideration. HbAl was lower in men (mean 10.94) compared with women (mean 11.39, P=0.004) and there was a positive correlation of HbAl in men with age (P= 0.046) and in women with duration of disease (P=0.005).</description><identifier>ISSN: 0141-0768</identifier><identifier>EISSN: 1758-1095</identifier><identifier>DOI: 10.1177/014107688507800706</identifier><identifier>PMID: 3891999</identifier><language>eng</language><publisher>England: SAGE Publications</publisher><subject>Age Factors ; Diabetes Mellitus, Type 1 - blood ; Diabetes Mellitus, Type 1 - drug therapy ; Female ; Glycated Hemoglobin A - analysis ; Humans ; Injections, Intravenous ; Insulin - administration & dosage ; Insulin - therapeutic use ; Male ; Sex Factors</subject><ispartof>Journal of the Royal Society of Medicine, 1985-07, Vol.78 (7), p.549-551</ispartof><rights>1985 The Royal Society of Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c437t-4da17a7da0ef0c170ac03bc5ac81424bd83bb35ef445090ba6080dd00271c9d3</citedby><cites>FETCH-LOGICAL-c437t-4da17a7da0ef0c170ac03bc5ac81424bd83bb35ef445090ba6080dd00271c9d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291177/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291177/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3891999$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Child, D F</creatorcontrib><creatorcontrib>Wood, Jane</creatorcontrib><creatorcontrib>Hudson, P R</creatorcontrib><creatorcontrib>Williams, C P</creatorcontrib><creatorcontrib>Roberts, D R</creatorcontrib><creatorcontrib>Smith, C</creatorcontrib><title>Multivariate Analysis of Glycosylated Haemoglobin in Insulin-Treated Diabetics</title><title>Journal of the Royal Society of Medicine</title><addtitle>J R Soc Med</addtitle><description>Glycosylated haemoglobin (HbAl), as an assessment of overall control, was estimated in 858 insulin-treated diabetics attending for changeover to U100 insulin in North East Wales. Details of age, sex, duration of diabetes, insulin regimen and monitoring method were recorded. Multivariate analysis revealed lower HbAl in patients receiving twice-daily (mean 11.01) as compared with once-daily insulin (11.42, P=0.011), but no difference was found between urine and blood glucose testers when other variables were taken into consideration. HbAl was lower in men (mean 10.94) compared with women (mean 11.39, P=0.004) and there was a positive correlation of HbAl in men with age (P= 0.046) and in women with duration of disease (P=0.005).</description><subject>Age Factors</subject><subject>Diabetes Mellitus, Type 1 - blood</subject><subject>Diabetes Mellitus, Type 1 - drug therapy</subject><subject>Female</subject><subject>Glycated Hemoglobin A - analysis</subject><subject>Humans</subject><subject>Injections, Intravenous</subject><subject>Insulin - administration & dosage</subject><subject>Insulin - therapeutic use</subject><subject>Male</subject><subject>Sex Factors</subject><issn>0141-0768</issn><issn>1758-1095</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kVtLAzEQhYMotVb_gCDsk29rJ3vL5kUoXqpQ9aXvYTabrSnpRpPdQv-9qS1FEYTAkJwz34QzhFxSuKGUsTHQjAIryjIHVgIwKI7IkLK8jCnw_JgMt4Z46zglZ94vIdx5kQ7IIC055ZwPyetLbzq9RqexU9GkRbPx2ke2iaZmI63fmPBeR0-oVnZhbKXbKJzn1vdGt_HcqW_5XmOlOi39OTlp0Hh1sa8jMn98mN89xbO36fPdZBbLLGVdnNVIGbIaQTUgKQOUkFYyR1nSLMmqukyrKs1Vk2U5cKiwgBLqGiBhVPI6HZHbHfajr1aqlqrtHBrx4fQK3UZY1OK30up3sbBrQRO-TS4ArvcAZz975Tux0l4qY7BVtveCFcGVsSQYk51ROuu9U81hCAWxRYm_SwhNVz-_d2jZpx708U73uFBiaXsXcvf_Eb8A98qRUg</recordid><startdate>198507</startdate><enddate>198507</enddate><creator>Child, D F</creator><creator>Wood, Jane</creator><creator>Hudson, P R</creator><creator>Williams, C P</creator><creator>Roberts, D R</creator><creator>Smith, C</creator><general>SAGE Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>198507</creationdate><title>Multivariate Analysis of Glycosylated Haemoglobin in Insulin-Treated Diabetics</title><author>Child, D F ; Wood, Jane ; Hudson, P R ; Williams, C P ; Roberts, D R ; Smith, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c437t-4da17a7da0ef0c170ac03bc5ac81424bd83bb35ef445090ba6080dd00271c9d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Age Factors</topic><topic>Diabetes Mellitus, Type 1 - blood</topic><topic>Diabetes Mellitus, Type 1 - drug therapy</topic><topic>Female</topic><topic>Glycated Hemoglobin A - analysis</topic><topic>Humans</topic><topic>Injections, Intravenous</topic><topic>Insulin - administration & dosage</topic><topic>Insulin - therapeutic use</topic><topic>Male</topic><topic>Sex Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Child, D F</creatorcontrib><creatorcontrib>Wood, Jane</creatorcontrib><creatorcontrib>Hudson, P R</creatorcontrib><creatorcontrib>Williams, C P</creatorcontrib><creatorcontrib>Roberts, D R</creatorcontrib><creatorcontrib>Smith, C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of the Royal Society of Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Child, D F</au><au>Wood, Jane</au><au>Hudson, P R</au><au>Williams, C P</au><au>Roberts, D R</au><au>Smith, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multivariate Analysis of Glycosylated Haemoglobin in Insulin-Treated Diabetics</atitle><jtitle>Journal of the Royal Society of Medicine</jtitle><addtitle>J R Soc Med</addtitle><date>1985-07</date><risdate>1985</risdate><volume>78</volume><issue>7</issue><spage>549</spage><epage>551</epage><pages>549-551</pages><issn>0141-0768</issn><eissn>1758-1095</eissn><abstract>Glycosylated haemoglobin (HbAl), as an assessment of overall control, was estimated in 858 insulin-treated diabetics attending for changeover to U100 insulin in North East Wales. Details of age, sex, duration of diabetes, insulin regimen and monitoring method were recorded. Multivariate analysis revealed lower HbAl in patients receiving twice-daily (mean 11.01) as compared with once-daily insulin (11.42, P=0.011), but no difference was found between urine and blood glucose testers when other variables were taken into consideration. HbAl was lower in men (mean 10.94) compared with women (mean 11.39, P=0.004) and there was a positive correlation of HbAl in men with age (P= 0.046) and in women with duration of disease (P=0.005).</abstract><cop>England</cop><pub>SAGE Publications</pub><pmid>3891999</pmid><doi>10.1177/014107688507800706</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Age Factors Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - drug therapy Female Glycated Hemoglobin A - analysis Humans Injections, Intravenous Insulin - administration & dosage Insulin - therapeutic use Male Sex Factors |
| title | Multivariate Analysis of Glycosylated Haemoglobin in Insulin-Treated Diabetics |
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