CD40 regulates the processing of NF-κB2 p100 to p52

The nf‐kb2 gene encodes the cytoplasmic NF‐κB inhibitory protein p100 from which the active p52 NF‐κB subunit is derived by proteasome‐mediated proteolysis. Ligands which stimulate p100 processing to p52 have not been defined. Here, ligation of CD40 on transfected 293 cells is shown to trigger p52 p...

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Veröffentlicht in:	The EMBO journal 2002-10, Vol.21 (20), p.5375-5385
Hauptverfasser:	Coope, H.J., Atkinson, P.G.P., Huhse, B., Belich, M., Janzen, J., Holman, M.J., Klaus, G.G.B., Johnston, L.H., Ley, S.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aly CD40 NF-κB2 NIK p100
Online-Zugang:	Volltext
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