Conjugated Linoleic Acid Promotes Human Adipocyte Insulin Resistance through NFκB-dependent Cytokine Production

We previously demonstrated that trans-10, cis-12 conjugated linoleic acid (CLA) reduced the triglyceride content of human adipocytes by activating mitogen-activated protein kinase kinase/extracellular signal-related kinase (MEK/ERK) signaling via interleukins (IL) 6 and 8. However, the upstream mech...

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Veröffentlicht in:	The Journal of biological chemistry 2005-11, Vol.280 (46), p.38445-38456
Hauptverfasser:	Chung, Soonkyu, Brown, J. Mark, Provo, J. Nathan, Hopkins, Robin, McIntosh, Michael K.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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