Arterial endothelial dysfunction in baboons fed a high-cholesterol, high-fat diet

BACKGROUND: Endothelial dysfunction signals the initiation and progression of atherosclerosis. Elevated LDL-cholesterol concentrations have been suggested to induce endothelial dysfunction, but direct in vivo evidence for the relation is still lacking. OBJECTIVE: We examined the hypothesis that a hi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of clinical nutrition 2005-10, Vol.82 (4), p.751-759
Hauptverfasser:	Shi, Qiang, Vandeberg, Jane F, Jett, Catherine, Rice, Karen, Leland, Michelle M, Talley, Leslie, Kushwaha, Rampratap S, Rainwater, David L, Vandeberg, John L, Wang, Xing Li
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Animals arteries atherosclerosis Biological and medical sciences Biomarkers - blood Biomarkers - metabolism Biopsy Chemokine CCL2 - metabolism Cholesterol cholesterol metabolism Cholesterol, Dietary - administration & dosage Cholesterol, Dietary - pharmacology Diet Dietary Fats - administration & dosage Dietary Fats - pharmacology Disease Models, Animal E-Selectin - metabolism endothelium Endothelium, Vascular - drug effects Endothelium, Vascular - physiopathology fat intake Feeding. Feeding behavior Female Femoral Artery - drug effects Femoral Artery - metabolism Femoral Artery - pathology Fundamental and applied biological sciences. Psychology high fat diet inflammation Inflammation - metabolism Inflammation Mediators - metabolism Interleukin-6 - metabolism Lipids - blood Male Monkeys & apes Nitric Oxide Synthase - metabolism Oils & fats Papio Primates risk factors Tumor Necrosis Factor-alpha - metabolism Vascular Cell Adhesion Molecule-1 - metabolism Vertebrates: anatomy and physiology, studies on body, several organs or systems
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!