Mediation of Epstein-Barr virus EBNA-LP transcriptional coactivation by Sp100

The Epstein–Barr virus (EBV) EBNA‐LP protein is important for EBV‐mediated B‐cell immortalization and is a potent gene‐specific coactivator of the viral transcriptional activator, EBNA2. The mechanism(s) by which EBNA‐LP functions as a coactivator remains an important question in the biology of EBV‐...

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Veröffentlicht in:	The EMBO journal 2005-10, Vol.24 (20), p.3565-3575
Hauptverfasser:	Ling, Paul D, Peng, Rong Sheng, Nakajima, Ayako, Yu, Jiang H, Tan, Jie, Moses, Stephanie M, Yang, Wei-Hong, Zhao, Bo, Kieff, Elliott, Bloch, Kenneth D, Bloch, Donald B
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Nuclear - analysis Antigens, Nuclear - genetics Antigens, Nuclear - metabolism Autoantigens - analysis Autoantigens - genetics Autoantigens - metabolism B-Lymphocytes - virology Cell Nucleus - chemistry Cell Nucleus - metabolism Cells, Cultured Chromobox Protein Homolog 5 Chromosomal Proteins, Non-Histone - metabolism EMBO09 EMBO24 Epstein-Barr virus Epstein-Barr Virus Nuclear Antigens - genetics Epstein-Barr Virus Nuclear Antigens - metabolism Gene Expression Regulation, Viral gene regulation Humans latency Leukemia nuclear bodies Nuclear Proteins - analysis Nuclear Proteins - genetics Nuclear Proteins - metabolism Protein Interaction Mapping Protein Structure, Tertiary Sequence Deletion Sp100 Transcription, Genetic Up-Regulation - genetics Viral Proteins - analysis Viral Proteins - metabolism
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