Identification of TSIX, Encoding an RNA Antisense to Human XIST, Reveals Differences from its Murine Counterpart: Implications for X Inactivation

X inactivation is the mammalian method for X-chromosome dosage compensation, but some features of this developmental process vary among mammals. Such species variations provide insights into the essential components of the pathway. Tsix encodes a transcript antisense to the murine Xist transcript an...

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Veröffentlicht in:	American journal of human genetics 2001-11, Vol.69 (5), p.951-960
Hauptverfasser:	Migeon, Barbara R., Chowdhury, Ashis K., Dunston, Jennifer A., McIntosh, Iain
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - genetics Animals Biological and medical sciences Cell Line Dosage Compensation, Genetic Embryo, Mammalian - metabolism Evolution, Molecular Fetus - metabolism General aspects. Genetic counseling Genomic Imprinting - genetics Humans Medical genetics Medical sciences Mice Molecular Sequence Data Open Reading Frames - genetics Placenta - metabolism RNA, Antisense - analysis RNA, Antisense - biosynthesis RNA, Antisense - genetics RNA, Antisense - isolation & purification RNA, Long Noncoding RNA, Untranslated - analysis RNA, Untranslated - biosynthesis RNA, Untranslated - genetics RNA, Untranslated - isolation & purification Sequence Deletion - genetics Sequence Homology, Nucleic Acid Species Specificity Stem Cells - metabolism Transcription Factors - genetics Transcription Initiation Site Transcription, Genetic Transgenes - genetics TSIX gene XIST gene
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