A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells

The mammalian dynamin-like protein DLP1/Drp1 has been shown to mediate both mitochondrial and peroxisomal fission. In this study, we have examined whether hFis1, a mammalian homologue of yeast Fis1, which has been shown to participate in mitochondrial fission by an interaction with DLP1/Drp1, is als...

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Veröffentlicht in:	Molecular biology of the cell 2005-11, Vol.16 (11), p.5077-5086
Hauptverfasser:	Koch, Annett, Yoon, Yisang, Bonekamp, Nina A, McNiven, Mark A, Schrader, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line, Tumor Cercopithecus aethiops COS Cells GTP Phosphohydrolases - metabolism Humans Membrane Proteins - chemistry Membrane Proteins - metabolism Membrane Proteins - physiology Microtubule-Associated Proteins - metabolism Mitochondria - metabolism Mitochondrial Proteins - metabolism Mitochondrial Proteins - physiology Peroxisomes - metabolism Rats RNA, Small Interfering - pharmacology Transfection
Online-Zugang:	Volltext
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