Neutropenia in cats with the Chediak-Higashi syndrome
Thirteen cats with Chediak-Higashi syndrome and 22 control cats from the same colony, were evaluated for neutropenia. The absolute neutrophil counts of the Chediak-Higashi syndrome cats were significantly less (P less than 0.05) than those of the control cats. It is concluded that Chediak-Higashi sy...
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Veröffentlicht in: | Canadian journal of veterinary research 1987-07, Vol.51 (3), p.407-408 |
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description | Thirteen cats with Chediak-Higashi syndrome and 22 control cats from the same colony, were evaluated for neutropenia. The absolute neutrophil counts of the Chediak-Higashi syndrome cats were significantly less (P less than 0.05) than those of the control cats. It is concluded that Chediak-Higashi syndrome cats, like Chediak-Higashi syndrome humans, have a neutropenia associated with the other manifestations of the syndrome. Lysozyme activity which was undetectable in the serum of both Chediak-Higashi syndrome and control cats was not of use for determining if the neutropenia was the result of neutrophil destruction. |
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The absolute neutrophil counts of the Chediak-Higashi syndrome cats were significantly less (P less than 0.05) than those of the control cats. It is concluded that Chediak-Higashi syndrome cats, like Chediak-Higashi syndrome humans, have a neutropenia associated with the other manifestations of the syndrome. Lysozyme activity which was undetectable in the serum of both Chediak-Higashi syndrome and control cats was not of use for determining if the neutropenia was the result of neutrophil destruction.</description><identifier>ISSN: 0830-9000</identifier><identifier>PMID: 3651899</identifier><language>eng</language><publisher>Canada</publisher><subject>Agranulocytosis - veterinary ; Animals ; Cat Diseases - blood ; Cats ; Chediak-Higashi syndrome ; Chediak-Higashi Syndrome - blood ; Chediak-Higashi Syndrome - veterinary ; disease models ; Female ; lysozyme ; Male ; Neutropenia - veterinary ; neutrophils</subject><ispartof>Canadian journal of veterinary research, 1987-07, Vol.51 (3), p.407-408</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1255348/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1255348/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3651899$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Prieur, D.J</creatorcontrib><creatorcontrib>Collier, L.L</creatorcontrib><title>Neutropenia in cats with the Chediak-Higashi syndrome</title><title>Canadian journal of veterinary research</title><addtitle>Can J Vet Res</addtitle><description>Thirteen cats with Chediak-Higashi syndrome and 22 control cats from the same colony, were evaluated for neutropenia. The absolute neutrophil counts of the Chediak-Higashi syndrome cats were significantly less (P less than 0.05) than those of the control cats. It is concluded that Chediak-Higashi syndrome cats, like Chediak-Higashi syndrome humans, have a neutropenia associated with the other manifestations of the syndrome. Lysozyme activity which was undetectable in the serum of both Chediak-Higashi syndrome and control cats was not of use for determining if the neutropenia was the result of neutrophil destruction.</description><subject>Agranulocytosis - veterinary</subject><subject>Animals</subject><subject>Cat Diseases - blood</subject><subject>Cats</subject><subject>Chediak-Higashi syndrome</subject><subject>Chediak-Higashi Syndrome - blood</subject><subject>Chediak-Higashi Syndrome - veterinary</subject><subject>disease models</subject><subject>Female</subject><subject>lysozyme</subject><subject>Male</subject><subject>Neutropenia - veterinary</subject><subject>neutrophils</subject><issn>0830-9000</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1987</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkE1Lw0AQhveg1Fr9CWJO3gKzX8nmIkhRKxQ9WM_LZLPbrOaj7iZK_72BFtHTDDwvzzvMCZmD4pAWAHBGzmN8B2B5xviMzHgmqSqKOZHPdhxCv7Odx8R3icEhJt9-qJOhtsmytpXHj3Tltxhrn8R9V4W-tRfk1GET7eVxLsjm4X6zXKXrl8en5d06dUzJIVWIwgErqVFonawMBaoM5SVgTgul6LTyrBC2dAUaAXklOKNS2VI5UTm-ILcH7W4sW1sZ2w0BG70LvsWw1z16_Z90vtbb_ktTJiUXahLcHAWh_xxtHHTro7FNg53tx6jVdFABnE_Bq79NvxXHP038-sAd9hq3wUf99sqAcmDA80xI_gPOmG0P</recordid><startdate>19870701</startdate><enddate>19870701</enddate><creator>Prieur, D.J</creator><creator>Collier, L.L</creator><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19870701</creationdate><title>Neutropenia in cats with the Chediak-Higashi syndrome</title><author>Prieur, D.J ; Collier, L.L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-f285t-8aa4f02b1c8aef5dc1018c13b0a71988113b3694ebf9ac407d432158eb8f4df3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1987</creationdate><topic>Agranulocytosis - veterinary</topic><topic>Animals</topic><topic>Cat Diseases - blood</topic><topic>Cats</topic><topic>Chediak-Higashi syndrome</topic><topic>Chediak-Higashi Syndrome - blood</topic><topic>Chediak-Higashi Syndrome - veterinary</topic><topic>disease models</topic><topic>Female</topic><topic>lysozyme</topic><topic>Male</topic><topic>Neutropenia - veterinary</topic><topic>neutrophils</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Prieur, D.J</creatorcontrib><creatorcontrib>Collier, L.L</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Canadian journal of veterinary research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Prieur, D.J</au><au>Collier, L.L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neutropenia in cats with the Chediak-Higashi syndrome</atitle><jtitle>Canadian journal of veterinary research</jtitle><addtitle>Can J Vet Res</addtitle><date>1987-07-01</date><risdate>1987</risdate><volume>51</volume><issue>3</issue><spage>407</spage><epage>408</epage><pages>407-408</pages><issn>0830-9000</issn><abstract>Thirteen cats with Chediak-Higashi syndrome and 22 control cats from the same colony, were evaluated for neutropenia. The absolute neutrophil counts of the Chediak-Higashi syndrome cats were significantly less (P less than 0.05) than those of the control cats. It is concluded that Chediak-Higashi syndrome cats, like Chediak-Higashi syndrome humans, have a neutropenia associated with the other manifestations of the syndrome. Lysozyme activity which was undetectable in the serum of both Chediak-Higashi syndrome and control cats was not of use for determining if the neutropenia was the result of neutrophil destruction.</abstract><cop>Canada</cop><pmid>3651899</pmid><tpages>2</tpages></addata></record> |
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subjects | Agranulocytosis - veterinary Animals Cat Diseases - blood Cats Chediak-Higashi syndrome Chediak-Higashi Syndrome - blood Chediak-Higashi Syndrome - veterinary disease models Female lysozyme Male Neutropenia - veterinary neutrophils |
title | Neutropenia in cats with the Chediak-Higashi syndrome |
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